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The chronic effects of KeenMind CDRI 08™ on cognitive function in healthy human subjects*
Abstract: Extracts of Bacopa monnieri have been reported to exert cognitive enhancing effects in animals. However, the effects on human cognition are inconclusive. This study examined the chronic effects of a special extract of Bacopa monnieri (KeenMind CDRI 08™) on cognitive function in healthy human subjects.
Methods: The study was a double-blind placebo-controlled independent-group design in which forty-six healthy adult volunteers aged between 18 and 60 years were randomly allocated to one of two treatment conditions, KeenMind (2 capsules) or placebo. Neuropsychological testing was conducted pre drug administration (baseline), and at 5 and 12 weeks post drug administration.
Results: KeenMind significantly improved speed of visual information processing measured by the IT task, learning rate and memory consolidation measured by the AVLT (P<0.05), compared to placebo, with maximal effects evident after 12 weeks.
Conclusions: These findings suggest that KeenMind may improve higher order cognitive processes that are critically dependent on the input of information from our environment such as learning and memory.
* Stough C et al. 2001. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacol. (Berl.), 156 (4): 481-484.